연구개발

[2018] 국학기공 프로그램이 여성노인의 심박변이도와 혈중 세로토닌 농도에 미치는 영향
  • 저자심준영, 유성모, 신재한, 강윤정, 연주헌
  • 저널명Korean Journal of Gerontological Social Welfare vol. 73(1), pp. 163-186
  • 초록본 연구는 국학기공 수련이 여성노인의 심박변이도(HRV)와 혈중 세로토닌 농도에 미치는 영향을 알아보는데 있다. 이를 위하여 여성노인 40명을 대상으로 실험집단 20명과 대조집단 20명으로 구분하고 실험집단에 대해 10주간, 주 2회, 회당 60분씩 국학기공 프로그램을 실시하였다. 분석결과, 심박변이도는 SDNN Index, RMSSD, pNN50에서 실험집단의 평균값이 대조집단에 비해 유의하게 높게 나타났으며, 우울의 지표가 되는 세로토닌 농도에서도 실험집단의 평균값이 유의하게 더 많은 증가를 보였다. 이러한 결과는 국학기공 수련이 여성노인의 스트레스에 대한 생리적 회복탄력성을 높이고, 우울감을 해소하여 생리적 건강상태를 개선하는데 도움을 줄 수 있음을 시사한다.

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[2017] 배꼽힐링(Belly Button Healing) 프로그램이 고등학생의 뇌파 활성도에 미치는 영향
  • 저자신재한, 강호중, 안승찬
  • 저널명한국산학기술학회논문지(Journal of the Korea Academia-Industrial cooperation Society) Vol. 18, No. 2 pp. 374-382, 2017
  • 초록본 연구에서는 고등학생을 대상으로 배꼽힐링 프로그램을 개발하고 적용한 후, 뇌파 검사를 통해 뇌파 활성도를 측정함으로써 그에 따른 효과성을 검증하는데 그 연구의 목적이 있다. 본 연구에 A고등학생 19명(남학생 8명, 여학생 11명)이 참여 하였으며 실험에 참여한 학생들은 2주 동안 매일 2회씩(아침, 저녁) 5분간 배꼽힐링 프로그램을 실시하였다. 효과검증을 위해 피험자의 각성상태 및 안정상태에서의 뇌파를 측정하였으며 스트루프 과제중의 뇌파의 변화를 관찰하였다. 이후 배꼽힐링을 약 5분간 실시하고 1분간의 휴식을 취한 후 동일한 과정을 반복하였다. 연구 결과, 배꼽힐링 프로그램을 통해 스트루프 과제 중 각성상태 대비 M-Beta파, H-Beta파, 그리고 Gamma파의 감소량이 줄어들었으며 안정상태 대비 Alpha파, SMR파의 감소량이 감소하는 것으로 나타났다. 이는 배꼽힐링을 통해 피험자들이 스트레스 상황에서의 집중력, 몰입력 등이 향상되었으며 심리적 안정상태도 유지한다는 것을 시사한다. 이는 학생들의 연구 후 인터뷰 내용과도 일치 한다. 따라서, 본 연구의 결론을 제시하면 다음과 같다. 첫째, 배꼽힐링 프로그램은 고등학생의 스트레스 해소에 효과가 있기 때문에, 학업 스트레스를 많이 받는 수험생을 대상으로 배꼽힐링 프로그램을 실시할 필요가 있다. 둘째, 배꼽힐링 프로그램은 고등학생의 집중력과 몰입력을 증가시키는 효과가 있기 때문에, 복잡하거나 어려운 특정 과제를 해결하기 전에 배꼽힐링 프로그램을 실시할 필요가 있다.

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[2013] The effect of meditation on brain structure: cortical thickness mapping and diffusion tensor imaging
  • 저자D.H.Kang, H.J.Jo, W.H.Jung, S.H.Kim, Y.H.Jung, C.H.Choi,
  • 저널명Social Cognitive and Affective Neuroscience 8, 27-33
  • 초록

    A convergent line of neuroscientific evidence suggests that meditation alters the functional and structural plasticity of distributed neural processes underlying attention and emotion. The purpose of this study was to examine the brain structural differences between a well-matched sample of longterm meditators and controls. We employed whole-brain cortical thickness analysis, based on magnetic resonance imaging, and diffusion tensor imaging to quantify white matter integrity in the brains of 46 experienced meditators compared with 46 matched meditation-naïve volunteers. Meditators, compared with controls, showed significantly greater cortical thickness in the anterior regions of the brain, located in frontal and temporal areas, including the medial prefrontal cortex, superior frontal cortex, temporal pole, and the middle and interior temporal cortices. Significantly thinner cortical thickness was found in the posterior regions of the brain, located in the parietal and occipital areas, including the postcentral cortex, inferior parietal cortex, middle occipital cortex, and posterior cingulate cortex. Moreover, in the region adjacent to the medial prefrontal cortex, both higher fractional anisotropy values and greater cortical thickness were observed. Our findings suggest that long-term meditators have structural differences in both gray and white matter.

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[2012] A Comparative Randomised Controlled Trial of the Effects of BrainWave Vibration Training, Iyengar Yoga, andMindfulness on Mood,Well-Being, and Salivary Cortisol
  • 저자Deborah Bowden, Claire Gaudry, Seung Chan An, John Gruzelier
  • 저널명Evidence-Based Complementary and Alternative Medicine Volume 2012, Article ID 234713, 13 pages
  • 초록This randomised trial compared the effects of BrainWave Vibration (BWV) training, which involves rhythmic yoga-like meditative exercises, with Iyengar yoga and Mindfulness. Iyengar provided a contrast for the physical components and mindfulness for the "mental" components of BWV. 35 healthy adults completed 10 75-minute classes of BWV, Iyengar, or Mindfulness over five weeks. Participants were assessed at pre- and post intervention for mood, sleep, mindfulness, absorption, health, memory, and salivary cortisol. Better overall mood and vitality followed both BWV and Iyengar training, while the BWV group alone had improved depression and sleep latency. Mindfulness produced a comparatively greater increase in absorption. All interventions improved stress and mindfulness, while no changes occurred in health, memory, or salivary cortisol. In conclusion, increased well-being followed training in all three practices, increased absorption was specific to Mindfulness, while BWV was unique in its benefits to depression and sleep latency, warranting further research.

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[2012] Influence of brain-derived neurotrophic factor and catechol O-methyl transferase polymorphisms on effects of meditation on plasma catecholamines and stress
  • 저자Y.H.JUNG, D.H.KANG, M.S.BYUN, G.S.SHIM, S.J.KWON, G.E.JANG, U.S.LEE, S.C.AN, J.H.JANG, J.S.KWON
  • 저널명Stress 15(1):97-104
  • 초록Meditation may show differential effects on stress and plasma catecholamines based on genetic polymorphisms in brainderived neurotrophic factor (BDNF) and catechol O-methyl transferase (COMT). Eighty adults (40 men, 40 women; mean age 26 years) who practiced meditation regularly and 57 healthy control adults (35 men, 22 women; mean age 26 years) participated. Plasma catecholamines (norepinephrine (NE), epinephrine (E), and dopamine (DA)) concentrations were measured, and a modified form of the Stress Response Inventory was administered. The results were analyzed using two-way analysis of covariance (ANCOVA) with control and meditation subjects, gene polymorphism as factors, and meditation duration as the covariate. Two-way ANCOVA showed a significant interaction between control and meditation subjects, and BDNF Val66Met polymorphism on DA/NE + DA/E (p=0.042) and NE/E + NE/DA (p=0.046) ratios. A significant interaction was found for control and meditation subjects with COMT Val158Met polymorphism and plasma NE concentrations (p=0.009). Post hoc ANCOVA in the meditation group, adjusted for meditation duration, showed significantly higher plasma NE concentrations for COMT Met carriers than COMT Val/Val subjects (p=0.025). Significant differences of stress levels were found between the control and meditation subjects in BDNF Val/Met (p<0.001) and BDNF Met/Met (p=0.003), whereas stress levels in the BDNF Val/Val genotype did not differ between the control and meditation groups. This is the first evidence that meditation produces different effects on plasma catecholamines according to BDNF or COMT polymorphisms.

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[2010] The effects of mind-body training on stress reduction, positive affect, and plasma catecholamines
  • 저자Y.H.Jung, D.H.Kang, J.H.Jang, H.Y.Park, M.S.Byun, S.J.Kwon, G.E.Jang, U.S.Lee, S. C.An, J.S.Kwon
  • 저널명Neuroscience Letters, 479, p138-142
  • 초록This study was designed to assess the association between stress, positive affect and catecholamine levels in meditation and control groups. The meditation group consisted of 67 subjects who regularly engaged in mind-body training of "Brain-Wave Vibration" and the control group consisted of 57 healthy subjects. Plasma catecholamine (norepinephrine (NE), epinephrine (E), and dopamine (DA)) levels were measured, and a modified form of the Stress Response Inventory (SRI-MF) and the Positive Affect and Negative Affect Scale (PANAS) were administered. The meditation group showed higher scores on positive affect (p = .019) and lower scores on stress (p < .001) compared with the control group. Plasma DA levels were also higher in the meditation (p = .031) than in the control group. The control group demonstrated a negative correlation between stress and positive affects (r =-.408, p = .002), whereas this correlation was not observed in the meditation group. The control group showed positive correlations between somatization and NE/E (r = .267, p = .045) and DA/E (r = .271, p = .042) ratios, whereas these correlations did not emerge in the meditation group. In conclusion, these results suggest that meditation as mind-body training is associated with lower stress, higher positive affect and higher plasma DA levels when comparing the meditation group with the control group. Thus, mind-body training may influence stress, positive affect and the sympathetic nervous system including DA activity.

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[2009] The Effect of the Brain Education Program on Emotional Intelligence, Stress, and Stress-Coping Strategies of Elementary School Students
  • 저자오미경, 김월순, 이성원, Rebecca Cheema, 이을순, 이승헌
  • 저널명아동교육 제18권 제1호 2009. Vol. 18, No. 1, 169~181
  • 초록Brain-oriented educational programs are increasingly popular. The purpose of this study was to investigate the impact of a classroom-based Brain Education program, which is strongly focused on elementary children`s emotional intelligence, perceived stress, and stress coping strategies. Twenty-seven fifth-grade elementary school students completed the Brain Education program over the course of a full academic year. Twenty-five students in a control group participated on Chinese writing classes. Pre-test post-test comparisons were conducted through repeated measures ANOVA, to evaluate the impact of the Brain Education program. The brain education program positively influenced emotional intelligence and the degree of perceived stress, and the stress coping strategies. Results are discussed in terms of possible mechanisms of benefit and recommendations for future research.

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[2007] Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder
  • 저자Sang Hyuk Lee, Seung Chan Ahn, Yu Jin Lee, Tae Kyu Choi, Ki Hwan Yook, Shin Young Suh
  • 저널명Journal of Psycholsomatic Research
  • 초록Objective The objective of this study was to examine the effectiveness of a meditation-based stress management program in patients with anxiety disorder. Methods Patients with anxiety disorder were randomly assigned to an 8-week clinical trial of either a meditation-based stress management program or an anxiety disorder education program. The Hamilton Anxiety Rating Scale (HAM-A), the Hamilton Depression Rating Scale (HAM-D), the State–Trait Anxiety Inventory (STAI), the Beck Depression Inventory, and the Symptom Checklist-90—Revised (SCL-90-R) were used to measure outcome at 0, 2, 4, and 8 weeks of the program. Results Compared to the education group, the meditation-based stress management group showed significant improvement in scores on all anxiety scales (HAM-A, P=.00; STAI state, P=.00; STAI trait, P=.00; anxiety subscale of SCL-90-R, P=.00) and in the SCL-90-R hostility subscale (P=.01). Findings on depression measures were inconsistent, with no significant improvement shown by subjects in the meditation-based stress management group compared to those in the education group. The meditation-based stress management group did not show significant improvement in somatization, obsessive–compulsive symptoms, and interpersonal sensitivity scores, or in the SCL-90-R phobic anxiety subscale compared to the education group. Conclusions A meditation-based stress management program can be effective in relieving anxiety symptoms in patients with anxiety disorder. However, well-designed, randomized, and controlled trials are needed to scientifically prove the worth of this intervention prior to treatment.

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[2007] 장생보법 훈련이 신체증상 지각 및 뇌 영역별 활성에 미치는 영향
  • 저자심준영,김홍기,이성원,이승헌
  • 저널명한국스포츠리서치. 2007, 제18권 4호, 통권 103호, pp. 413-424
  • 초록This study aims to examine the influence of 'Jangsaeng Walking' on activation conditions of brain and 'psychosomatic symptom' through comparison of 'common walking' and 'Jangsaeng Walking' with 40 women between 30 and 50 years old. 20 of 40 selected women were assigned to experimental group and 20 others to control group and experimental group conducted Jangsaeng Walking for 30 min. per semester through four times a week for 8 weeks. Electroencephalogram (EEG) was measured for 5 min. through 3 times at the first stability period, the second walking period and the third stability period. Electrode was attached to measured parts such as Fp1, Fp2, F3, F4, T3, T4, P3 and P4 by International 10/20 electrode system and relative power and cross correlation analysis were conducted. Questionnaire of psychosomatic symptoms was conducted before measuring EEG and comparison between groups was performed. As a result of repeated measure two way ANOVA, relative power by each frequency band of EEG showed significant difference between groups in alpha wave and gamma wave and relative power of alpha wave and gamma wave and cross correlation coefficient were analyzed. In the analysis of relative power, alpha wave showed significant difference between groups in Fp1, Fp2, T3, T4 and P3 and gamma wave did in Fp1, Fp2, F3, F4, T3 and P3. Experimental group showed significant decrease in alpha wave at the 2nd walking period compared to the first stability period, but gamma wave showed significant increase. In cross correlation analysis, alpha wave showed significant differences in total 11 electrode pairs and gamma wave did in 12 electrode pairs. In particular, at the second walking period, experimental group showed increase of functional cooperation between electrode pairs to parietal lobe centering around frontal lobe compared to control group. Changes of psychosomatic symptoms showed significant decrease at 'headache' and 'digestion' of four sub-factors in experimental group and it was found that perception of psychosomatic symptoms was improved.

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[2006] Neural correlates of superior intelligence : Stronger recruitment of posterior parietal cortex.
  • 저자K.H.Lee, Y.Y.Choi, Jeremy R. Gray, S.H.Cho, J.H.Chae, S.H.Lee, K.G.Kim,
  • 저널명NeuroImage. Vol 29(2). 578~586.
  • 초록General intelligence (g) is a common factor in diverse cognitive abilities and a major influence on life outcomes. Neuroimaging studies in adults suggest that the lateral prefrontal and parietal cortices play a crucial role in related cognitive activities including fluid reasoning, the control of attention, and working memory. Here, we investigated the neural bases for intellectual giftedness (superior-g) in adolescents, using fMRI. The participants consisted of a superior-g group (n = 18, mean RAPM = 33.9 T 0.8, >99%) from the national academy for gifted adolescents and the control group (n = 18, mean RAPM = 22.8 T 1.6, 60%) from local high schools in Korea (mean age = 16.5 T 0.8). fMRI data were acquired while they performed two reasoning tasks with high and low g-loadings. In both groups, the high g-loaded tasks specifically increased regional activity in the bilateral fronto-parietal network including the lateral prefrontal, anterior cingulate, and posterior parietal cortices. However, the regional activations of the superior-g group were significantly stronger than those of the control group, especially in the posterior parietal cortex. Moreover, regression analysis revealed that activity of the superior and intraparietal cortices (BA 7/40) strongly covaried with individual differences in g (r = 0.71 to 0.81). A correlated vectors analysis implicated bilateral posterior parietal areas in g. These results suggest that superior-g may not be due to the recruitment of additional brain regions but to the functional facilitation of the fronto-parietal network particularly driven by the posterior parietal activation.

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[2006] The effects of environmental luminance on colour perception in heightened sensory perception(HSP) trained children.
  • 저자S.W.Kim, S.H.Ahn, D.P.Jang, J.H.Ku, Sumners D.P., U.S.Lee, Z.H.Cho S.H.Lee,
  • 저널명Acta Physiologica, Vol 186, supplement 1, 249. Poster presentation
  • 초록

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[2006] Stimuls intensity dependence of colour perception by heightened sensory perception(HSP) trained children.
  • 저자S.H.Ahn, S.W.Kim, D.P.Jang, J.H.Ku, Sumners D.P., U.S.Lee, Z.H.Cho S.H.Lee
  • 저널명Acta Physiologica, Vol 186, supplement 1, 250. Poster presentation
  • 초록

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